All Phenotypes Ltbr<m3Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ltbr^m3Btlr
mutation 3, Bruce Beutler
MGI:6197810

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ltbr^m3Btlr/Ltbr^m3Btlr	C57BL/6J-Ltbr^m3Btlr	MGI:6197813

Allelic Composition	Ltbr^m3Btlr/Ltbr^m3Btlr
Genetic Background	C57BL/6J-Ltbr^m3Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ltbr^m3Btlr mutation (0 available); any Ltbr mutation (47 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

increased NK T cell number ( J:264642 )

• reduced killing of beta-2-microglobulin-deficient NK cell targets compared to wild-type littermates

immune system

increased NK T cell number ( J:264642 )

• reduced killing of beta-2-microglobulin-deficient NK cell targets compared to wild-type littermates

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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