Phenotypes associated with this allele

• Allele Symbol: Prkdc^m12Btlr
• Allele Name: mutation 12, Bruce Beutler
• Allele ID: MGI:6198357
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prkdc^m12Btlr/Prkdc^m12Btlr	C57BL/6J-Prkdc^m12Btlr	MGI:6198360

Genotype
MGI:6198360

hm1

• Allelic Composition: Prkdc^m12Btlr/Prkdc^m12Btlr
• Genetic Background: C57BL/6J-Prkdc^m12Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased B cell number ( J:264708 )

decreased B-1 B cell number ( J:264708 )

increased NK cell number ( J:264708 )

increased central memory CD4-positive, alpha-beta T cell number ( J:264708 )

increased effector memory CD4-positive, alpha-beta T cell number ( J:264708 )

increased central memory CD8 positive, alpha-beta T cell number ( J:264708 )

decreased CD8-positive, naive alpha-beta T cell number ( J:264708 )

decreased T cell number ( J:264708 )

decreased CD4-positive, alpha-beta T cell number ( J:264708 )

decreased CD8-positive, alpha-beta T cell number ( J:264708 )

decreased NK T cell number ( J:264708 )

decreased single-positive T cell number ( J:264708 )

hematopoietic system

decreased B cell number ( J:264708 )

decreased B-1 B cell number ( J:264708 )

increased NK cell number ( J:264708 )

increased central memory CD4-positive, alpha-beta T cell number ( J:264708 )

increased effector memory CD4-positive, alpha-beta T cell number ( J:264708 )

increased central memory CD8 positive, alpha-beta T cell number ( J:264708 )

decreased CD8-positive, naive alpha-beta T cell number ( J:264708 )

decreased T cell number ( J:264708 )

decreased CD4-positive, alpha-beta T cell number ( J:264708 )

decreased CD8-positive, alpha-beta T cell number ( J:264708 )

decreased NK T cell number ( J:264708 )

decreased single-positive T cell number ( J:264708 )