Phenotypes associated with this allele

• Allele Symbol: Tbl1xr1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:6199116
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tbl1xr1^tm1b(EUCOMM)Hmgu/Tbl1xr1^tm1b(EUCOMM)Hmgu	C57BL/6N-Tbl1xr1^tm1b(EUCOMM)Hmgu/Ieg	MGI:6288763
ht2	Tbl1xr1^tm1b(EUCOMM)Hmgu/Tbl1xr1^+	C57BL/6N-Tbl1xr1^tm1b(EUCOMM)Hmgu/Ieg	MGI:6288762

Genotype
MGI:6288763

hm1

• Allelic Composition: Tbl1xr1^{tm1b(EUCOMM)Hmgu}/Tbl1xr1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Tbl1xr1^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0744_3_D01

Data Sources

IMPC Data for Tbl1xr1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - HMGU

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:6288762

ht2

• Allelic Composition: Tbl1xr1^{tm1b(EUCOMM)Hmgu}/Tbl1xr1⁺
• Genetic Background: C57BL/6N-Tbl1xr1^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0744_3_D01

Data Sources

IMPC Data for Tbl1xr1

behavior/neurological

abnormal startle reflex ( J:211773 )

IMPC - HMGU

cardiovascular system

increased heart weight ( J:211773 )

IMPC - HMGU

digestive/alimentary system

enlarged cecum ( J:211773 )

♂

IMPC - HMGU

endocrine/exocrine glands

enlarged ovary ( J:211773 )

♀

IMPC - HMGU

growth/size/body

increased heart weight ( J:211773 )

IMPC - HMGU

enlarged ovary ( J:211773 )

♀

IMPC - HMGU

enlarged liver ( J:211773 )

♂

IMPC - HMGU

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

increased blood urea nitrogen level ( J:211773 )

♂

IMPC - HMGU

integument

absent vibrissae ( J:211773 )

♀

IMPC - HMGU

liver/biliary system

abnormal liver morphology ( J:211773 )

♀

IMPC - HMGU

enlarged liver ( J:211773 )

♂

IMPC - HMGU

reproductive system

enlarged ovary ( J:211773 )

♀

IMPC - HMGU