All Phenotypes Tbl1xr1<tm1b(EUCOMM)Hmgu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tbl1xr1^{tm1b(EUCOMM)Hmgu}
targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
MGI:6199116

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tbl1xr1^{tm1b(EUCOMM)Hmgu}/Tbl1xr1^{tm1b(EUCOMM)Hmgu}	C57BL/6N-Tbl1xr1^{tm1b(EUCOMM)Hmgu}/Ieg	MGI:6288763
ht2	Tbl1xr1^{tm1b(EUCOMM)Hmgu}/Tbl1xr1⁺	C57BL/6N-Tbl1xr1^{tm1b(EUCOMM)Hmgu}/Ieg	MGI:6288762

Allelic Composition	Tbl1xr1^{tm1b(EUCOMM)Hmgu}/Tbl1xr1^{tm1b(EUCOMM)Hmgu}
Genetic Background	C57BL/6N-Tbl1xr1^{tm1b(EUCOMM)Hmgu}/Ieg
Cell Lines	HEPD0744_3_D01

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tbl1xr1^{tm1b(EUCOMM)Hmgu} mutation (1 available); any Tbl1xr1 mutation (321 available)

Data Sources

IMPC Data for Tbl1xr1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - HMGU

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HMGU

Allelic Composition	Tbl1xr1^{tm1b(EUCOMM)Hmgu}/Tbl1xr1⁺
Genetic Background	C57BL/6N-Tbl1xr1^{tm1b(EUCOMM)Hmgu}/Ieg
Cell Lines	HEPD0744_3_D01

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tbl1xr1^{tm1b(EUCOMM)Hmgu} mutation (1 available); any Tbl1xr1 mutation (321 available)

Data Sources

IMPC Data for Tbl1xr1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal startle reflex ( J:211773 )

IMPC - HMGU

cardiovascular system

increased heart weight ( J:211773 )

IMPC - HMGU

digestive/alimentary system

enlarged cecum ( J:211773 )

IMPC - HMGU

endocrine/exocrine glands

enlarged ovary ( J:211773 )

IMPC - HMGU

growth/size/body

increased heart weight ( J:211773 )

IMPC - HMGU

enlarged ovary ( J:211773 )

IMPC - HMGU

enlarged liver ( J:211773 )

IMPC - HMGU

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

increased blood urea nitrogen level ( J:211773 )

IMPC - HMGU

decreased circulating HDL cholesterol level ( J:211773 )

IMPC - HMGU

increased circulating phosphate level ( J:211773 )

IMPC - HMGU

integument

absent vibrissae ( J:211773 )

IMPC - HMGU

liver/biliary system

abnormal liver morphology ( J:211773 )

IMPC - HMGU

enlarged liver ( J:211773 )

IMPC - HMGU

reproductive system

enlarged ovary ( J:211773 )

IMPC - HMGU

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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