All Phenotypes Ptpn6<M5Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ptpn6^M5Btlr
mutation 5, Bruce Beutler
MGI:6199169

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ptpn6^M5Btlr/Ptpn6^M5Btlr	C57BL/6J-Ptpn6^M5Btlr	MGI:6199171

Allelic Composition	Ptpn6^M5Btlr/Ptpn6^M5Btlr
Genetic Background	C57BL/6J-Ptpn6^M5Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptpn6^M5Btlr mutation (0 available); any Ptpn6 mutation (49 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased B cell number ( J:265075 )

decreased B-1 B cell number ( J:265075 )

decreased IgD level ( J:265075 )

• on peripheral blood B cells

decreased IgM level ( J:265075 )

• on peripheral blood B cells

hematopoietic system

decreased B cell number ( J:265075 )

decreased B-1 B cell number ( J:265075 )

decreased IgD level ( J:265075 )

• on peripheral blood B cells

decreased IgM level ( J:265075 )

• on peripheral blood B cells

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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