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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Itgb2m2Btlr
mutation 2, Bruce Beutler
MGI:6199651
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Itgb2m2Btlr/Itgb2m2Btlr C57BL/6J-Itgb2m2Btlr MGI:6199653


Genotype
MGI:6199653
hm1
Allelic
Composition		 Itgb2m2Btlr/Itgb2m2Btlr
Genetic
Background		 C57BL/6J-Itgb2m2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itgb2m2Btlr mutation (0 available); any Itgb2 mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased interferon-beta secretion ( J:265125 )
• from isolated peritoneal macrophages upon stimulation with double-stranded DNA (dsDNA)




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory