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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Prkcdm2Btlr
mutation 2, Bruce Beutler
MGI:6199966
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Prkcdm2Btlr/Prkcdm2Btlr C57BL/6J-Prkcdm2Btlr MGI:6199968


Genotype
MGI:6199968
hm1
Allelic
Composition		 Prkcdm2Btlr/Prkcdm2Btlr
Genetic
Background		 C57BL/6J-Prkcdm2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prkcdm2Btlr mutation (0 available); any Prkcd mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased susceptibility to induced colitis ( J:265146 )
• increased susceptibility to DSS-induced colitis on days 7 and 10 post-DSS treatment
increased IgM level ( J:265146 )
• increased T-independent antibody response to 4-hydroxy-3-nitrophenylacetyl-Ficoll (NP-Ficoll)
enhanced humoral immune response ( J:265146 )
• increased T-independent antibody response to 4-hydroxy-3-nitrophenylacetyl-Ficoll (NP-Ficoll)

digestive/alimentary system
increased susceptibility to induced colitis ( J:265146 )
• increased susceptibility to DSS-induced colitis on days 7 and 10 post-DSS treatment

hematopoietic system
increased IgM level ( J:265146 )
• increased T-independent antibody response to 4-hydroxy-3-nitrophenylacetyl-Ficoll (NP-Ficoll)




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory