Phenotypes associated with this allele

• Allele Symbol: Aicda^m1Btlr
• Allele Name: mutation 1, Bruce Beutler
• Allele ID: MGI:6199978
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Aicda^m1Btlr/Aicda^m1Btlr	C57BL/6J-Aicda^m1Btlr	MGI:6199980

Genotype
MGI:6199980

hm1

• Allelic Composition: Aicda^m1Btlr/Aicda^m1Btlr
• Genetic Background: C57BL/6J-Aicda^m1Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

decreased IgE level ( J:265155 )

• in the serum

• seven days after second OVA/Alum challenge

increased IgM level ( J:265155 )

• diminished T-dependent antibody response to ovalbumin administered with aluminum hydroxide

• diminished T-dependent antibody responses to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)

immune system

abnormal humoral immune response ( J:265155 )

• diminished T-dependent antibody response to ovalbumin administered with aluminum hydroxide

• diminished T-dependent antibody responses to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)

decreased IgE level ( J:265155 )

• in the serum

• seven days after second OVA/Alum challenge

increased IgM level ( J:265155 )

• diminished T-dependent antibody response to ovalbumin administered with aluminum hydroxide

• diminished T-dependent antibody responses to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)