Phenotypes associated with this allele

• Allele Symbol: Rasgrp1^m2Btlr
• Allele Name: mutation 2, Bruce Beutler
• Allele ID: MGI:6200009
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rasgrp1^m2Btlr/Rasgrp1^m2Btlr	C57BL/6J-Rasgrp1^m2Btlr	MGI:6200011

Genotype
MGI:6200011

hm1

• Allelic Composition: Rasgrp1^m2Btlr/Rasgrp1^m2Btlr
• Genetic Background: C57BL/6J-Rasgrp1^m2Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

increased NK cell number ( J:265163 )

increased central memory CD4-positive, alpha-beta T cell number ( J:265163 )

increased effector memory CD4-positive, alpha-beta T cell number ( J:265163 )

increased central memory CD8 positive, alpha-beta T cell number ( J:265163 )

increased effector memory CD8-positive, alpha-beta T cell number ( J:265163 )

decreased CD8-positive, naive alpha-beta T cell number ( J:265163 )

decreased T cell number ( J:265163 )

decreased CD4-positive, alpha-beta T cell number ( J:265163 )

decreased CD8-positive, alpha-beta T cell number ( J:265163 )

decreased single-positive T cell number ( J:265163 )

immune system

increased NK cell number ( J:265163 )

increased central memory CD4-positive, alpha-beta T cell number ( J:265163 )

increased effector memory CD4-positive, alpha-beta T cell number ( J:265163 )

increased central memory CD8 positive, alpha-beta T cell number ( J:265163 )

increased effector memory CD8-positive, alpha-beta T cell number ( J:265163 )

decreased CD8-positive, naive alpha-beta T cell number ( J:265163 )

decreased T cell number ( J:265163 )

decreased CD4-positive, alpha-beta T cell number ( J:265163 )

decreased CD8-positive, alpha-beta T cell number ( J:265163 )

decreased single-positive T cell number ( J:265163 )