Phenotypes associated with this allele

• Allele Symbol: Dicer1^m1Btlr
• Allele Name: mutation 1, Bruce Beutler
• Allele ID: MGI:6200045
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dicer1^m1Btlr/Dicer1^m1Btlr	C57BL/6J-Dicer1^m1Btlr	MGI:6200047

Genotype
MGI:6200047

hm1

• Allelic Composition: Dicer1^m1Btlr/Dicer1^m1Btlr
• Genetic Background: C57BL/6J-Dicer1^m1Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

increased B-1 B cell number ( J:265172 )

increased effector memory CD4-positive, alpha-beta T cell number ( J:265172 )

increased central memory CD8 positive, alpha-beta T cell number ( J:265172 )

increased effector memory CD8-positive, alpha-beta T cell number ( J:265172 )

decreased CD8-positive, naive alpha-beta T cell number ( J:265172 )

decreased T cell number ( J:265172 )

decreased CD4-positive, alpha-beta T cell number ( J:265172 )

decreased CD8-positive, alpha-beta T cell number ( J:265172 )

decreased single-positive T cell number ( J:265172 )

immune system

increased B-1 B cell number ( J:265172 )

increased effector memory CD4-positive, alpha-beta T cell number ( J:265172 )

increased central memory CD8 positive, alpha-beta T cell number ( J:265172 )

increased effector memory CD8-positive, alpha-beta T cell number ( J:265172 )

decreased CD8-positive, naive alpha-beta T cell number ( J:265172 )

decreased T cell number ( J:265172 )

decreased CD4-positive, alpha-beta T cell number ( J:265172 )

decreased CD8-positive, alpha-beta T cell number ( J:265172 )

decreased single-positive T cell number ( J:265172 )