All Phenotypes Mlh1<m1Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mlh1^m1Btlr
mutation 1, Bruce Beutler
MGI:6200234

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mlh1^m1Btlr/Mlh1^m1Btlr	C57BL/6J-Mlh1^m1Btlr	MGI:6200236

Allelic Composition	Mlh1^m1Btlr/Mlh1^m1Btlr
Genetic Background	C57BL/6J-Mlh1^m1Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mlh1^m1Btlr mutation (0 available); any Mlh1 mutation (44 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

increased IgM level ( J:265206 )

• diminished T-dependent antibody responses to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)

immune system

abnormal humoral immune response ( J:265206 )

• diminished T-dependent antibody responses to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)

increased IgM level ( J:265206 )

• diminished T-dependent antibody responses to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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