Phenotypes associated with this allele

• Allele Symbol: Dnajc3^m1Btlr
• Allele Name: mutation 1, Bruce Beutler
• Allele ID: MGI:6200312
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dnajc3^m1Btlr/Dnajc3^m1Btlr	C57BL/6J-Dnajc3^m1Btlr	MGI:6200314

Genotype
MGI:6200314

hm1

• Allelic Composition: Dnajc3^m1Btlr/Dnajc3^m1Btlr
• Genetic Background: C57BL/6J-Dnajc3^m1Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

increased susceptibility to induced colitis ( J:265248 )

• dextran sodium sulfate (DSS)-induced colitis

increased T cell number ( J:265248 )

increased CD4-positive, alpha-beta T cell number ( J:265248 )

increased CD8-positive, alpha-beta memory T cell number ( J:265248 )

increased single-positive T cell number ( J:265248 )

growth/size/body

decreased body weight ( J:265248 )

digestive/alimentary system

increased susceptibility to induced colitis ( J:265248 )

• dextran sodium sulfate (DSS)-induced colitis

hematopoietic system

increased T cell number ( J:265248 )

increased CD4-positive, alpha-beta T cell number ( J:265248 )

increased CD8-positive, alpha-beta memory T cell number ( J:265248 )

increased single-positive T cell number ( J:265248 )