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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Mlkltm1.1Wsa
targeted mutation 1.1, Warren S Alexander
MGI:6251546
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Faddtm1Mpa/Faddtm1Mpa
Mlkltm1.1Wsa/Mlkltm1.1Wsa
Otulintm1c(EUCOMM)Hmgu/Otulintm1c(EUCOMM)Hmgu
Tg(KRT14-cre)1Cgn/0
involves: C57BL/6 * C57BL/6N * DBA/2 MGI:7256619
cn2
Mlkltm1.1Wsa/Mlkltm1.1Wsa
Otulintm1c(EUCOMM)Hmgu/Otulintm1c(EUCOMM)Hmgu
Tg(KRT14-cre)1Cgn/0
involves: C57BL/6 * C57BL/6N * DBA/2 MGI:7256622


Genotype
MGI:7256619
cn1
Allelic
Composition
Faddtm1Mpa/Faddtm1Mpa
Mlkltm1.1Wsa/Mlkltm1.1Wsa
Otulintm1c(EUCOMM)Hmgu/Otulintm1c(EUCOMM)Hmgu
Tg(KRT14-cre)1Cgn/0
Genetic
Background
involves: C57BL/6 * C57BL/6N * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Faddtm1Mpa mutation (0 available); any Fadd mutation (18 available)
Mlkltm1.1Wsa mutation (0 available); any Mlkl mutation (32 available)
Otulintm1c(EUCOMM)Hmgu mutation (0 available); any Otulin mutation (24 available)
Tg(KRT14-cre)1Cgn mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
N
• normal circulating inflammatory cytokine levels

integument
N
• no skin lesions and normal epidermal thickness




Genotype
MGI:7256622
cn2
Allelic
Composition
Mlkltm1.1Wsa/Mlkltm1.1Wsa
Otulintm1c(EUCOMM)Hmgu/Otulintm1c(EUCOMM)Hmgu
Tg(KRT14-cre)1Cgn/0
Genetic
Background
involves: C57BL/6 * C57BL/6N * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mlkltm1.1Wsa mutation (0 available); any Mlkl mutation (32 available)
Otulintm1c(EUCOMM)Hmgu mutation (0 available); any Otulin mutation (24 available)
Tg(KRT14-cre)1Cgn mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• delineated inflamed skin lesions on back
• no skin lesions in tail

integument
N
• no skin lesions and normal epidermal thickness in tail
• delineated inflamed skin lesions on back
• no skin lesions in tail





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory