skeleton
Allele Symbol Allele Name Allele ID |
Usp34em1Qyn endonuclease-mediated mutation 1, Quan Yuan MGI:6256462 |
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Summary |
2 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• slowed healing that never achieves comparable healing as in wild-type mice after fracture with reduced trabecular bone volume to trabecular volume, diminished trabeculae number and trabecular thickness, and a large amount of callus cartilage
• drilled holes are only partially filled after 2 weeks compared to complete bridging in control mice with reduced bone mineral density and bone volume to trabecular volume
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• slowed healing that never achieves comparable healing as in wild-type mice after fracture with reduced trabecular bone volume to trabecular volume, diminished trabeculae number and trabecular thickness, and a large amount of callus cartilage
• drilled holes are only partially filled after 2 weeks compared to complete bridging in control mice with reduced bone mineral density and bone volume to trabecular volume
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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