Phenotypes associated with this allele

• Allele Symbol: Itsn1^em1(IMPC)H
• Allele Name: endonuclease-mediated mutation 1, Harwell
• Allele ID: MGI:6257669
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Itsn1^em1(IMPC)H/Itsn1^em1(IMPC)H	C57BL/6NTac-Itsn1^em1(IMPC)H/H	MGI:6492902
ht2	Itsn1^em1(IMPC)H/Itsn1^+	C57BL/6NTac-Itsn1^em1(IMPC)H/H	MGI:6492901

Genotype
MGI:6492902

hm1

• Allelic Composition: Itsn1^em1(IMPC)H/Itsn1^em1(IMPC)H
• Genetic Background: C57BL/6NTac-Itsn1^em1(IMPC)H/H

Data Sources

IMPC Data for Itsn1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

limb grasping ( J:211773 )

♂

IMPC - HAR

abnormal gait ( J:211773 )

♀

IMPC - HAR

homeostasis/metabolism

increased circulating iron level ( J:211773 )

♀

IMPC - HAR

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - HAR

increased circulating amylase level ( J:211773 )

♂

IMPC - HAR

increased circulating serum albumin level ( J:211773 )

♂

IMPC - HAR

increased circulating total protein level ( J:211773 )

IMPC - HAR

integument

abnormal skin coloration ( J:211773 )

♀

IMPC - HAR

nervous system

decreased prepulse inhibition ( J:211773 )

IMPC - HAR

Genotype
MGI:6492901

ht2

• Allelic Composition: Itsn1^em1(IMPC)H/Itsn1⁺
• Genetic Background: C57BL/6NTac-Itsn1^em1(IMPC)H/H

Data Sources

IMPC Data for Itsn1

behavior/neurological

decreased exploration in new environment ( J:211773 )

♀

IMPC - HAR