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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nhsl2em1(IMPC)Tcp
endonuclease-mediated mutation 1, The Centre for Phenogenomics
MGI:6257670
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nhsl2em1(IMPC)Tcp/Nhsl2em1(IMPC)Tcp C57BL/6N-Nhsl2em1(IMPC)Tcp/Tcp MGI:6492980
ot2
 		Nhsl2em1(IMPC)Tcp/Y C57BL/6N-Nhsl2em1(IMPC)Tcp/Tcp MGI:6492979


Genotype
MGI:6492980
hm1
Allelic
Composition		 Nhsl2em1(IMPC)Tcp/Nhsl2em1(IMPC)Tcp
Genetic
Background		 C57BL/6N-Nhsl2em1(IMPC)Tcp/Tcp
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nhsl2em1(IMPC)Tcp mutation (2 available); any Nhsl2 mutation (12 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system

immune system

integument

reproductive system
small uterus ( J:211773 )
IMPC - TCP

vision/eye




Genotype
MGI:6492979
ot2
Allelic
Composition		 Nhsl2em1(IMPC)Tcp/Y
Genetic
Background		 C57BL/6N-Nhsl2em1(IMPC)Tcp/Tcp
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nhsl2em1(IMPC)Tcp mutation (2 available); any Nhsl2 mutation (12 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
enlarged urinary bladder ( J:211773 )
IMPC - TCP
enlarged spleen ( J:211773 )
IMPC - TCP

hematopoietic system
enlarged spleen ( J:211773 )
IMPC - TCP

immune system
enlarged spleen ( J:211773 )
IMPC - TCP

integument
thick skin ( J:211773 )
IMPC - TCP

renal/urinary system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory