vision/eye
N |
• On this DBA/2J congenic background, which is wild type at the Jak3 locus, there are no retinal abnormalities even at 6 months of age
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Allele Symbol Allele Name Allele ID |
Crb1em2Boc endonuclease-mediated mutation 2, Bo Chang MGI:6259426 |
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Summary |
2 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
Early-onset multifocal depigmented retinal lesions in Crb1em2Boc/Crb1em2Boc Jak3m1J/Jak3m1J mice on a C57BL/6J background (A, B) but normal retinas in Crb1em2Boc/Crb1em2Boc mice on a DBA/2J background (C,D).
N |
• On this DBA/2J congenic background, which is wild type at the Jak3 locus, there are no retinal abnormalities even at 6 months of age
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
Early-onset multifocal depigmented retinal lesions in Crb1em2Boc/Crb1em2Boc Jak3m1J/Jak3m1J mice on a C57BL/6J background (A, B) but normal retinas in Crb1em2Boc/Crb1em2Boc mice on a DBA/2J background (C,D).
• early-onset multifocal depigmented retinal lesions, significant by 4 weeks of age
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• early-onset multifocal depigmented retinal lesions, significant by 4 weeks of age
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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