Phenotypes associated with this allele

• Allele Symbol: Miox^tm1Ysk
• Allele Name: targeted mutation 1, Yashpal S Kanwar
• Allele ID: MGI:6267379
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Miox^tm1Ysk/Miox^tm1Ysk Hprt1^tm1(Pck1-cre)Vhh/Hprt1^+	B6.129-Miox^tm1Ysk Hprt1^tm1(Pck1-cre)Vhh	MGI:6267414

Genotype
MGI:6267414

cn1

• Allelic Composition: Miox^tm1Ysk/Miox^tm1Ysk; Hprt1^{tm1(Pck1-cre)Vhh}/Hprt1⁺
• Genetic Background: B6.129-Miox^tm1Ysk Hprt1^{tm1(Pck1-cre)Vhh}

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased susceptibility to injury ( J:266834 )

• mice exhibit ameliorated cisplatin-induced acute kidney injury with reduced weight loss and minimal elevation of serum creatinine or urea levels, and mild cytolysis of tubular cells and loss of brush border but no renal tubular cell apoptosis or induction of reactive oxygen species generation compared with wild-type mice

growth/size/body

decreased susceptibility to weight loss ( J:266834 )

• induced by cisplatin