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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Myo1dm2Btlr
mutation 2, Bruce Beutler
MGI:6268406
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Myo1dm2Btlr/Myo1dm2Btlr C57BL/6J-Myo1dm2Btlr MGI:6268692
ht2
 		Myo1dm1Btlr/Myo1dm2Btlr C57BL/6J-Myo1dm1Btlr/Myo1dm2Btlr MGI:6268700


Genotype
MGI:6268692
hm1
Allelic
Composition		 Myo1dm2Btlr/Myo1dm2Btlr
Genetic
Background		 C57BL/6J-Myo1dm2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myo1dm2Btlr mutation (1 available); any Myo1d mutation (61 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
increased susceptibility to induced colitis ( J:267525 )
• at 7 and 10 days after DSS exposure

immune system
increased susceptibility to induced colitis ( J:267525 )
• at 7 and 10 days after DSS exposure




Genotype
MGI:6268700
ht2
Allelic
Composition		 Myo1dm1Btlr/Myo1dm2Btlr
Genetic
Background		 C57BL/6J-Myo1dm1Btlr/Myo1dm2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myo1dm1Btlr mutation (1 available); any Myo1d mutation (61 available)
Myo1dm2Btlr mutation (1 available); any Myo1d mutation (61 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
increased susceptibility to induced colitis ( J:267525 )
• after 9 days of DSS treatment

growth/size/body
increased susceptibility to weight loss ( J:267525 )
• after DSS-treatment

immune system
increased susceptibility to induced colitis ( J:267525 )
• after 9 days of DSS treatment




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory