Phenotypes associated with this allele

• Allele Symbol: Myo1d^em1Btlr
• Allele Name: endonuclease-mediated mutation 1, Bruce Beutler
• Allele ID: MGI:6268688
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Myo1d^em1Btlr/Myo1d^em1Btlr	C57BL/6J-Myo1d^em1Btlr	MGI:6268698

Genotype
MGI:6268698

hm1

• Allelic Composition: Myo1d^em1Btlr/Myo1d^em1Btlr
• Genetic Background: C57BL/6J-Myo1d^em1Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

increased susceptibility to colitis induced morbidity/mortality ( J:267525 )

• 10 days after DSS treatment

digestive/alimentary system

digestive/alimentary phenotype ( J:267525 )

N • mice exhibit normal intestinal differentiation

increased susceptibility to induced colitis ( J:267525 )

• with increased weight loss at 6 and 8 days after DSS treatment and death by day 10

increased susceptibility to colitis induced morbidity/mortality ( J:267525 )

• 10 days after DSS treatment

growth/size/body

increased susceptibility to weight loss ( J:267525 )

• increased weight loss at 6 and 8 days after DSS treatment

immune system

increased susceptibility to induced colitis ( J:267525 )

• with increased weight loss at 6 and 8 days after DSS treatment and death by day 10

increased susceptibility to colitis induced morbidity/mortality ( J:267525 )

• 10 days after DSS treatment