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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Thraem4Ffla
endonuclease-mediated mutation 4, Frederic Flamant
MGI:6272836
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Thraem4Ffla/Thra+ C57BL/6-Thraem4Ffla MGI:6317184


Genotype
MGI:6317184
ht1
Allelic
Composition		 Thraem4Ffla/Thra+
Genetic
Background		 C57BL/6-Thraem4Ffla
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Thraem4Ffla mutation (0 available); any Thra mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
skeleton phenotype ( J:268664 )
N
• mice exhibit normal long bone lengths and trabecular thickness
delayed endochondral bone ossification ( J:268664 )
• incomplete ossification in long bones at P15 with persistence of thick cartilage plates at the extremities

homeostasis/metabolism
homeostasis/metabolism phenotype ( J:268664 )
N
• mice exhibit normal free T3 levels and hemoglobin content




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory