Phenotypes associated with this allele

• Allele Symbol: Ube3a^{em1(IMPC)Hmgu}
• Allele Name: endonuclease-mediated mutation 1, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:6273955
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ube3a^em1(IMPC)Hmgu/Ube3a^em1(IMPC)Hmgu	C57BL/6N-Ube3a^em1(IMPC)Hmgu/Ieg	MGI:6408751
ht2	Ube3a^em1(IMPC)Hmgu/Ube3a^+	C57BL/6N-Ube3a^em1(IMPC)Hmgu/Ieg	MGI:6408750

Genotype
MGI:6408751

hm1

• Allelic Composition: Ube3a^{em1(IMPC)Hmgu}/Ube3a^{em1(IMPC)Hmgu}
• Genetic Background: C57BL/6N-Ube3a^{em1(IMPC)Hmgu}/Ieg

Data Sources

IMPC Data for Ube3a

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased total body fat amount ( J:211773 )

♀

IMPC - HMGU

behavior/neurological

decreased exploration in new environment ( J:211773 )

IMPC - HMGU

decreased food intake ( J:211773 )

IMPC - HMGU

decreased vertical activity ( J:211773 )

IMPC - HMGU

decreased locomotor activity ( J:211773 )

IMPC - HMGU

hyperactivity ( J:211773 )

IMPC - HMGU

endocrine/exocrine glands

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - HMGU

growth/size/body

decreased lean body mass ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

decreased respiratory quotient ( J:211773 )

IMPC - HMGU

reproductive system

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - HMGU

skeleton

decreased bone mineral content ( J:211773 )

♀

IMPC - HMGU

Genotype
MGI:6408750

ht2

• Allelic Composition: Ube3a^{em1(IMPC)Hmgu}/Ube3a⁺
• Genetic Background: C57BL/6N-Ube3a^{em1(IMPC)Hmgu}/Ieg

Data Sources

IMPC Data for Ube3a

behavior/neurological

decreased food intake ( J:211773 )

♂

IMPC - HMGU

decreased locomotor activity ( J:211773 )

IMPC - HMGU

hematopoietic system

increased hematocrit ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

decreased respiratory quotient ( J:211773 )

♂

IMPC - HMGU