Phenotypes associated with this allele

• Allele Symbol: Neurod2^{em1(IMPC)Hmgu}
• Allele Name: endonuclease-mediated mutation 1, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:6273956
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Neurod2^em1(IMPC)Hmgu/Neurod2^em1(IMPC)Hmgu	C57BL/6N-Neurod2^em1(IMPC)Hmgu/Ieg	MGI:6408530
ht2	Neurod2^em1(IMPC)Hmgu/Neurod2^+	C57BL/6N-Neurod2^em1(IMPC)Hmgu/Ieg	MGI:6408529

Genotype
MGI:6408530

hm1

• Allelic Composition: Neurod2^{em1(IMPC)Hmgu}/Neurod2^{em1(IMPC)Hmgu}
• Genetic Background: C57BL/6N-Neurod2^{em1(IMPC)Hmgu}/Ieg

Data Sources

IMPC Data for Neurod2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased total body fat amount ( J:211773 )

♀

IMPC - HMGU

behavior/neurological

abnormal behavior ( J:211773 )

IMPC - HMGU

increased exploration in new environment ( J:211773 )

IMPC - HMGU

decreased food intake ( J:211773 )

IMPC - HMGU

increased anxiety-related response ( J:211773 )

IMPC - HMGU

increased thigmotaxis ( J:211773 )

IMPC - HMGU

decreased startle reflex ( J:211773 )

IMPC - HMGU

increased grip strength ( J:211773 )

IMPC - HMGU

abnormal locomotor behavior ( J:211773 )

♀

IMPC - HMGU

decreased vertical activity ( J:211773 )

IMPC - HMGU

decreased locomotor activity ( J:211773 )

IMPC - HMGU

hyperactivity ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

decreased circulating calcium level ( J:211773 )

IMPC - HMGU

decreased respiratory quotient ( J:211773 )

IMPC - HMGU

integument

abnormal coat appearance ( J:211773 )

♂

IMPC - HMGU

limbs/digits/tail

short tibia ( J:211773 )

♀

IMPC - HMGU

nervous system

decreased prepulse inhibition ( J:211773 )

♀

IMPC - HMGU

skeleton

short tibia ( J:211773 )

♀

IMPC - HMGU

vision/eye

abnormal cornea morphology ( J:211773 )

IMPC - HMGU

cornea deposits ( J:211773 )

IMPC - HMGU

cornea opacity ( J:211773 )

♀

IMPC - HMGU

abnormal lens morphology ( J:211773 )

IMPC - HMGU

cataract ( J:211773 )

IMPC - HMGU

narrow eye opening ( J:211773 )

IMPC - HMGU

abnormal retina morphology ( J:211773 )

IMPC - HMGU

Genotype
MGI:6408529

ht2

• Allelic Composition: Neurod2^{em1(IMPC)Hmgu}/Neurod2⁺
• Genetic Background: C57BL/6N-Neurod2^{em1(IMPC)Hmgu}/Ieg

Data Sources

IMPC Data for Neurod2

behavior/neurological

increased exploration in new environment ( J:211773 )

IMPC - HMGU

integument

abnormal coat appearance ( J:211773 )

♂

IMPC - HMGU

vision/eye

abnormal lens morphology ( J:211773 )

♀

IMPC - HMGU

narrow eye opening ( J:211773 )

IMPC - HMGU