Phenotypes associated with this allele

• Allele Symbol: Cngb3^cpfl10
• Allele Name: cone photoreceptor function loss 10
• Allele ID: MGI:6274478
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cngb3^cpfl10/Cngb3^cpfl10	involves: 129S6/SvEvTac * C57BL/6J	MGI:6275192

Genotype
MGI:6275192

hm1

• Allelic Composition: Cngb3^cpfl10/Cngb3^cpfl10
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

decreased retina cone cell number ( J:269211 )

• progressive and more severe than expected with normal aging

• not as severe as in mice homozygous for Cngb3^tm1Dgen

retina cone cell degeneration ( J:269211 )

abnormal cone electrophysiology ( J:269211 )

• completely absent or substantially reduced light-adapted cone responses

• however, dark-adapted rod response is normal

nervous system

decreased retina cone cell number ( J:269211 )

• progressive and more severe than expected with normal aging

• not as severe as in mice homozygous for Cngb3^tm1Dgen

retina cone cell degeneration ( J:269211 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
achromatopsia 3		DOID:0110008	OMIM:262300	J:269211