Phenotypes associated with this allele

• Allele Symbol: Marchf6^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:6274924
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Marchf6^tm1b(EUCOMM)Hmgu/Marchf6^tm1b(EUCOMM)Hmgu	C57BL/6N-Marchf6^tm1b(EUCOMM)Hmgu/Ccpcz	MGI:6461421

Genotype
MGI:6461421

hm1

• Allelic Composition: Marchf6^{tm1b(EUCOMM)Hmgu}/Marchf6^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Marchf6^{tm1b(EUCOMM)Hmgu}/Ccpcz
• Cell Lines: HEPD0773_3_A09

Data Sources

IMPC Data for Marchf6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

IMPC - CCP-IMG

increased freezing behavior ( J:211773 )

♀

IMPC - CCP-IMG

decreased grip strength ( J:211773 )

IMPC - CCP-IMG

hyperactivity ( J:211773 )

♀

IMPC - CCP-IMG

craniofacial

abnormal snout morphology ( J:211773 )

♂

IMPC - CCP-IMG

endocrine/exocrine glands

abnormal testis morphology ( J:211773 )

♂

IMPC - CCP-IMG

small testis ( J:211773 )

♂

IMPC - CCP-IMG

growth/size/body

abnormal snout morphology ( J:211773 )

♂

IMPC - CCP-IMG

decreased body weight ( J:211773 )

IMPC - CCP-IMG

hematopoietic system

thrombocytopenia ( J:211773 )

IMPC - CCP-IMG

decreased mean platelet volume ( J:211773 )

♀

IMPC - CCP-IMG

decreased CD4-positive, alpha-beta T cell number ( J:211773 )

♂

IMPC - CCP-IMG

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

♂

IMPC - CCP-IMG

increased circulating alkaline phosphatase level ( J:211773 )

♂

IMPC - CCP-IMG

increased circulating aspartate transaminase level ( J:211773 )

♂

IMPC - CCP-IMG

impaired glucose tolerance ( J:211773 )

♀

IMPC - CCP-IMG

immune system

decreased CD4-positive, alpha-beta T cell number ( J:211773 )

♂

IMPC - CCP-IMG

limbs/digits/tail

short tibia ( J:211773 )

IMPC - CCP-IMG

nervous system

decreased prepulse inhibition ( J:211773 )

♂

IMPC - CCP-IMG

reproductive system

abnormal testis morphology ( J:211773 )

♂

IMPC - CCP-IMG

small testis ( J:211773 )

♂

IMPC - CCP-IMG

male infertility ( J:211773 )

♂

IMPC - CCP-IMG

respiratory system

decreased lung elastance ( J:211773 )

♂

IMPC - CCP-IMG

decreased airway resistance ( J:211773 )

♂

IMPC - CCP-IMG

skeleton

short tibia ( J:211773 )

IMPC - CCP-IMG