reproductive system
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• percentage of sperm with a crooked/bent midpiece is significantly increased
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• most cauda epididymal sperm exhibit deformed head morphology
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• percentage of acephalic/headless sperm is significantly increased
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• a significant drop in the number of late stage spermatids is observed, starting from step 7
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• a significant drop in the number of late stage spermatids is observed, starting from step 7
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• at 6 weeks of age, average sperm count in the cauda epididymis is severely reduced
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• a dramatic decrease in sperm motility is observed
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• a slight but significant decrease in testis weight is observed at 3 months of age
• however, testis size and weight are normal at 6 weeks of age
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• development of late stage haploid spermatids is impaired
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• cauda epididymis shows an accumulation of immature germ cells and aberrant sperm
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• subfertile males produced an average of 1.7 pups per litter
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• half of the 2-month-old males examined were completely sterile
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• half of the 2-month-old males examined produced very small litters
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cellular
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• percentage of sperm with a crooked/bent midpiece is significantly increased
|
|
• most cauda epididymal sperm exhibit deformed head morphology
|
|
• percentage of acephalic/headless sperm is significantly increased
|
|
• a significant drop in the number of late stage spermatids is observed, starting from step 7
|
|
• a significant drop in the number of late stage spermatids is observed, starting from step 7
|
|
• at 6 weeks of age, average sperm count in the cauda epididymis is severely reduced
|
|
• a dramatic decrease in sperm motility is observed
|
endocrine/exocrine glands
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• a slight but significant decrease in testis weight is observed at 3 months of age
• however, testis size and weight are normal at 6 weeks of age
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