All Phenotypes Btg4<em3Hyfn> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Btg4^em3Hyfn
endonuclease-mediated mutation 3, Heng-Yu Fan
MGI:6276547

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Btg4^em1Hyfn/Btg4^em3Hyfn	Not Specified	MGI:7859723

Allelic Composition	Btg4^em1Hyfn/Btg4^em3Hyfn
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Btg4^em1Hyfn mutation (0 available); any Btg4 mutation (11 available)
Btg4^em3Hyfn mutation (0 available); any Btg4 mutation (11 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

female infertility ( J:245369 )

• mutant females are sterile

cellular

maternal effect ( J:245369 )

• fertilized oocytes derived from mutant females are arrested at the 1- or 2-cell stage

homeostasis/metabolism

abnormal metabolism ( J:245369 )

• maternal transcripts that are normally degraded during oocyte maturation are stabilized in mutant oocytes and zygotes, indicating that BTG4 functions through the CCR4NOT deadenylase in triggering decay of maternal mRNA

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24