Phenotypes associated with this allele

• Allele Symbol: Stim1^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6276841
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Stim1^em1(IMPC)Mbp/Stim1^em1(IMPC)Mbp	C57BL/6N-Stim1^em1(IMPC)Mbp/MbpMmucd	MGI:6408684
ht2	Stim1^em1(IMPC)Mbp/Stim1^+	C57BL/6N-Stim1^em1(IMPC)Mbp/MbpMmucd	MGI:6408683

Genotype
MGI:6408684

hm1

• Allelic Composition: Stim1^em1(IMPC)Mbp/Stim1^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Stim1^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Stim1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal blood vessel morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

embryo

abnormal placenta morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

vision/eye

microphthalmia ( J:211773 )

IMPC - UCD

Genotype
MGI:6408683

ht2

• Allelic Composition: Stim1^em1(IMPC)Mbp/Stim1⁺
• Genetic Background: C57BL/6N-Stim1^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Stim1

behavior/neurological

decreased exploration in new environment ( J:211773 )

♀

IMPC - UCD

cardiovascular system

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

embryo

embryonic growth retardation ( J:211773 )

IMPC - UCD

abnormal placenta morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - UCD

enlarged kidney ( J:211773 )

♂

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

hematopoietic system

increased leukocyte cell number ( J:211773 )

♀

IMPC - UCD

increased neutrophil cell number ( J:211773 )

♀

IMPC - UCD

increased lymphocyte cell number ( J:211773 )

♀

IMPC - UCD

abnormal spleen morphology ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

immune system

increased leukocyte cell number ( J:211773 )

♀

IMPC - UCD

increased neutrophil cell number ( J:211773 )

♀

IMPC - UCD

increased lymphocyte cell number ( J:211773 )

♀

IMPC - UCD

abnormal spleen morphology ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

abnormal lymph node morphology ( J:211773 )

♀

IMPC - UCD

enlarged lymph nodes ( J:211773 )

♀

IMPC - UCD

integument

abnormal skin morphology ( J:211773 )

♀

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♀

IMPC - UCD

enlarged kidney ( J:211773 )

♂

IMPC - UCD

small kidney ( J:211773 )

♀

IMPC - UCD

vision/eye

abnormal eye morphology ( J:211773 )

♀

IMPC - UCD

cataract ( J:211773 )

IMPC - UCD

microphthalmia ( J:211773 )

IMPC - UCD

abnormal vitreous body morphology ( J:211773 )

IMPC - UCD