Phenotypes associated with this allele

• Allele Symbol: Brap^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6276845
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Brap^em1(IMPC)Mbp/Brap^em1(IMPC)Mbp	C57BL/6NCrl-Brap^em1(IMPC)Mbp/Mmucd	MGI:6288358
ht2	Brap^em1(IMPC)Mbp/Brap^+	C57BL/6NCrl-Brap^em1(IMPC)Mbp/Mmucd	MGI:6394258

Genotype
MGI:6288358

hm1

• Allelic Composition: Brap^em1(IMPC)Mbp/Brap^em1(IMPC)Mbp
• Genetic Background: C57BL/6NCrl-Brap^em1(IMPC)Mbp/Mmucd

Data Sources

IMPC Data for Brap

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal neural tube morphology ( J:211773 )

IMPC - UCD

abnormal neural tube closure ( J:211773 )

♂

IMPC - UCD

mortality/aging

prenatal lethality prior to heart atrial septation ( J:211773 )

IMPC - UCD

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

nervous system

abnormal neural tube morphology ( J:211773 )

IMPC - UCD

abnormal neural tube closure ( J:211773 )

♂

IMPC - UCD

Genotype
MGI:6394258

ht2

• Allelic Composition: Brap^em1(IMPC)Mbp/Brap⁺
• Genetic Background: C57BL/6NCrl-Brap^em1(IMPC)Mbp/Mmucd

Data Sources

IMPC Data for Brap

behavior/neurological

increased freezing behavior ( J:211773 )

♂

IMPC - UCD

cardiovascular system

abnormal blood vessel morphology ( J:211773 )

IMPC - UCD

hemorrhage ( J:211773 )

IMPC - UCD

embryo

embryonic growth retardation ( J:211773 )

IMPC - UCD

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - UCD

homeostasis/metabolism

edema ( J:211773 )

IMPC - UCD

immune system

abnormal lymph node morphology ( J:211773 )

♂

IMPC - UCD

enlarged lymph nodes ( J:211773 )

♂

IMPC - UCD