Phenotypes associated with this allele

• Allele Symbol: Slc12a5^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6276849
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc12a5^em1(IMPC)Mbp/Slc12a5^em1(IMPC)Mbp	C57BL/6N-Slc12a5^em1(IMPC)Mbp/MbpMmucd	MGI:6408657
ht2	Slc12a5^em1(IMPC)Mbp/Slc12a5^+	C57BL/6N-Slc12a5^em1(IMPC)Mbp/MbpMmucd	MGI:6461660

Genotype
MGI:6408657

hm1

• Allelic Composition: Slc12a5^em1(IMPC)Mbp/Slc12a5^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Slc12a5^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Slc12a5

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal blood vessel morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

♂

IMPC - UCD

hemorrhage ( J:211773 )

IMPC - UCD

embryo

abnormal placenta morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

♂

IMPC - UCD

homeostasis/metabolism

edema ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

vision/eye

microphthalmia ( J:211773 )

IMPC - UCD

Genotype
MGI:6461660

ht2

• Allelic Composition: Slc12a5^em1(IMPC)Mbp/Slc12a5⁺
• Genetic Background: C57BL/6N-Slc12a5^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Slc12a5

digestive/alimentary system

abnormal colon morphology ( J:211773 )

♂

IMPC - UCD

abnormal duodenum morphology ( J:211773 )

♂

IMPC - UCD

abnormal jejunum morphology ( J:211773 )

♂

IMPC - UCD

abnormal stomach morphology ( J:211773 )

♂

IMPC - UCD

embryo

embryonic growth retardation ( J:211773 )

IMPC - UCD

abnormal placenta morphology ( J:211773 )

IMPC - UCD

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - UCD

enlarged spleen ( J:211773 )

♂

IMPC - UCD

hematopoietic system

abnormal spleen morphology ( J:211773 )

♂

IMPC - UCD

enlarged spleen ( J:211773 )

♂

IMPC - UCD

small spleen ( J:211773 )

♀

IMPC - UCD

homeostasis/metabolism

impaired glucose tolerance ( J:211773 )

♀

IMPC - UCD

immune system

abnormal spleen morphology ( J:211773 )

♂

IMPC - UCD

enlarged spleen ( J:211773 )

♂

IMPC - UCD

small spleen ( J:211773 )

♀

IMPC - UCD

integument

abnormal skin morphology ( J:211773 )

IMPC - UCD

renal/urinary system

small kidney ( J:211773 )

♀

IMPC - UCD

skeleton

decreased bone mineral content ( J:211773 )

♀

IMPC - UCD