Phenotypes associated with this allele

• Allele Symbol: Tnfrsf11b^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6276873
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tnfrsf11b^em1(IMPC)Mbp/Tnfrsf11b^em1(IMPC)Mbp	C57BL/6N-Tnfrsf11b^em1(IMPC)Mbp/MbpMmucd	MGI:6461758

Genotype
MGI:6461758

hm1

• Allelic Composition: Tnfrsf11b^em1(IMPC)Mbp/Tnfrsf11b^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Tnfrsf11b^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Tnfrsf11b

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased grip strength ( J:211773 )

♀

IMPC - UCD

abnormal gait ( J:211773 )

♂

IMPC - UCD

decreased locomotor activity ( J:211773 )

IMPC - UCD

endocrine/exocrine glands

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - UCD

growth/size/body

decreased body length ( J:211773 )

♀

IMPC - UCD

enlarged kidney ( J:211773 )

♂

IMPC - UCD

enlarged spleen ( J:211773 )

♂

IMPC - UCD

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - UCD

hematopoietic system

enlarged spleen ( J:211773 )

♂

IMPC - UCD

small spleen ( J:211773 )

♂

IMPC - UCD

homeostasis/metabolism

increased circulating phosphate level ( J:211773 )

IMPC - UCD

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - UCD

immune system

enlarged spleen ( J:211773 )

♂

IMPC - UCD

small spleen ( J:211773 )

♂

IMPC - UCD

enlarged lymph nodes ( J:211773 )

♂

IMPC - UCD

integument

abnormal skin morphology ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

♀

IMPC - UCD

nervous system

abnormal brain morphology ( J:211773 )

♀

IMPC - UCD

decreased brain size ( J:211773 )

♀

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - UCD

enlarged kidney ( J:211773 )

♂

IMPC - UCD

urinary bladder obstruction ( J:211773 )

♂

IMPC - UCD

reproductive system

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - UCD

blind uterus ( J:211773 )

♀

IMPC - UCD

skeleton

abnormal bone structure ( J:211773 )

♀

IMPC - UCD

decreased bone mineral content ( J:211773 )

IMPC - UCD

decreased bone mineral density ( J:211773 )

IMPC - UCD

vision/eye

abnormal eye morphology ( J:211773 )

♀

IMPC - UCD

cornea opacity ( J:211773 )

♀

IMPC - UCD

abnormal vitreous body morphology ( J:211773 )

♀

IMPC - UCD

anophthalmia ( J:211773 )

♀

IMPC - UCD