Phenotypes associated with this allele

• Allele Symbol: Tgfbr3^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6276920
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tgfbr3^em1(IMPC)Mbp/Tgfbr3^em1(IMPC)Mbp	C57BL/6N-Tgfbr3^em1(IMPC)Mbp/MbpMmucd	MGI:6408715
ht2	Tgfbr3^em1(IMPC)Mbp/Tgfbr3^+	C57BL/6N-Tgfbr3^em1(IMPC)Mbp/MbpMmucd	MGI:6408714

Genotype
MGI:6408715

hm1

• Allelic Composition: Tgfbr3^em1(IMPC)Mbp/Tgfbr3^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Tgfbr3^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Tgfbr3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal blood vessel morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

hemorrhage ( J:211773 )

IMPC - UCD

embryo

embryonic growth retardation ( J:211773 )

♂

IMPC - UCD

abnormal placenta morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

growth/size/body

embryonic growth retardation ( J:211773 )

♂

IMPC - UCD

homeostasis/metabolism

edema ( J:211773 )

IMPC - UCD

liver/biliary system

abnormal liver size ( J:211773 )

IMPC - UCD

pale liver ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

Genotype
MGI:6408714

ht2

• Allelic Composition: Tgfbr3^em1(IMPC)Mbp/Tgfbr3⁺
• Genetic Background: C57BL/6N-Tgfbr3^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Tgfbr3

embryo

abnormal placenta morphology ( J:211773 )

IMPC - UCD

growth/size/body

enlarged kidney ( J:211773 )

♂

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - UCD

enlarged kidney ( J:211773 )

♂

IMPC - UCD

vision/eye

microphthalmia ( J:211773 )

IMPC - UCD