Phenotypes associated with this allele

• Allele Symbol: Cacna2d1^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6276924
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cacna2d1^em1(IMPC)Mbp/Cacna2d1^em1(IMPC)Mbp	C57BL/6N-Cacna2d1^em1(IMPC)Mbp/MbpMmucd	MGI:6408269

Genotype
MGI:6408269

hm1

• Allelic Composition: Cacna2d1^em1(IMPC)Mbp/Cacna2d1^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Cacna2d1^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Cacna2d1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

enhanced contextual conditioning behavior ( J:211773 )

IMPC - UCD

decreased exploration in new environment ( J:211773 )

♀

IMPC - UCD

abnormal freezing behavior ( J:211773 )

♀

IMPC - UCD

increased freezing behavior ( J:211773 )

IMPC - UCD

decreased startle reflex ( J:211773 )

IMPC - UCD

decreased locomotor activity ( J:211773 )

♂

IMPC - UCD

hematopoietic system

increased monocyte cell number ( J:211773 )

♀

IMPC - UCD

abnormal spleen morphology ( J:211773 )

♂

IMPC - UCD

small spleen ( J:211773 )

♂

IMPC - UCD

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

IMPC - UCD

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - UCD

impaired glucose tolerance ( J:211773 )

IMPC - UCD

immune system

increased monocyte cell number ( J:211773 )

♀

IMPC - UCD

abnormal spleen morphology ( J:211773 )

♂

IMPC - UCD

small spleen ( J:211773 )

♂

IMPC - UCD

nervous system

decreased prepulse inhibition ( J:211773 )

IMPC - UCD

skeleton

decreased bone mineral content ( J:211773 )

♀

IMPC - UCD