Phenotypes associated with this allele

• Allele Symbol: Crtac1^em1(IMPC)H
• Allele Name: endonuclease-mediated mutation 1, Harwell
• Allele ID: MGI:6276953
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Crtac1^em1(IMPC)H/Crtac1^em1(IMPC)H	C57BL/6NTac-Crtac1^em1(IMPC)H/H	MGI:6696698

Genotype
MGI:6696698

hm1

• Allelic Composition: Crtac1^em1(IMPC)H/Crtac1^em1(IMPC)H
• Genetic Background: C57BL/6NTac-Crtac1^em1(IMPC)H/H

Data Sources

IMPC Data for Crtac1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased grip strength ( J:211773 )

♀

IMPC - HAR

abnormal locomotor behavior ( J:211773 )

IMPC - HAR

neoplasm

neoplasm ( J:322410 )

N • 10 days after being tail vein dosed with B16-F0 mouse melanoma cells that have been stably transfected with a vector carrying the Lrrn4cl cDNA (F0_LRN), mice show no significant differences in the number of pulmonary metastatic colonies relative to wild-type controls, suggesting that, in mice, LRRN4CL does not mediate an enhanced metastatic pulmonary colonization phenotype through binding to CRTAC1