Phenotypes associated with this allele

• Allele Symbol: Maf^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6276966
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Maf^em1(IMPC)Mbp/Maf^em1(IMPC)Mbp	C57BL/6N-Maf^em1(IMPC)Mbp/MbpMmucd	MGI:6408490
ht2	Maf^em1(IMPC)Mbp/Maf^+	C57BL/6N-Maf^em1(IMPC)Mbp/MbpMmucd	MGI:6408489

Genotype
MGI:6408490

hm1

• Allelic Composition: Maf^em1(IMPC)Mbp/Maf^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Maf^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Maf

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal blood vessel morphology ( J:211773 )

♀

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

embryo

embryonic growth retardation ( J:211773 )

♀

IMPC - UCD

abnormal placenta morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

growth/size/body

embryonic growth retardation ( J:211773 )

♀

IMPC - UCD

homeostasis/metabolism

edema ( J:211773 )

IMPC - UCD

liver/biliary system

abnormal liver size ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

vision/eye

microphthalmia ( J:211773 )

IMPC - UCD

Genotype
MGI:6408489

ht2

• Allelic Composition: Maf^em1(IMPC)Mbp/Maf⁺
• Genetic Background: C57BL/6N-Maf^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Maf

behavior/neurological

increased freezing behavior ( J:211773 )

♀

IMPC - UCD

increased grip strength ( J:211773 )

♀

IMPC - UCD

cardiovascular system

abnormal heart morphology ( J:211773 )

♂

IMPC - UCD

enlarged heart ( J:211773 )

♂

IMPC - UCD

embryo

abnormal placenta morphology ( J:211773 )

IMPC - UCD

endocrine/exocrine glands

abnormal ovary morphology ( J:211773 )

♀

IMPC - UCD

enlarged ovary ( J:211773 )

♀

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - UCD

enlarged ovary ( J:211773 )

♀

IMPC - UCD

enlarged kidney ( J:211773 )

♂

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

hematopoietic system

abnormal spleen morphology ( J:211773 )

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

small spleen ( J:211773 )

♀

IMPC - UCD

homeostasis/metabolism

increased circulating bilirubin level ( J:211773 )

♀

IMPC - UCD

immune system

abnormal spleen morphology ( J:211773 )

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

small spleen ( J:211773 )

♀

IMPC - UCD

liver/biliary system

abnormal liver morphology ( J:211773 )

♀

IMPC - UCD

small liver ( J:211773 )

♀

IMPC - UCD

nervous system

decreased prepulse inhibition ( J:211773 )

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - UCD

enlarged kidney ( J:211773 )

♂

IMPC - UCD

small kidney ( J:211773 )

♂

IMPC - UCD

urinary bladder obstruction ( J:211773 )

♂

IMPC - UCD

reproductive system

abnormal ovary morphology ( J:211773 )

♀

IMPC - UCD

enlarged ovary ( J:211773 )

♀

IMPC - UCD

vision/eye

cataract ( J:211773 )

♀

IMPC - UCD

microphthalmia ( J:211773 )

IMPC - UCD

abnormal vitreous body morphology ( J:211773 )

♀

IMPC - UCD