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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pax6em1(IMPC)Mbp
endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
MGI:6277040
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pax6em1(IMPC)Mbp/Pax6em1(IMPC)Mbp C57BL/6N-Pax6em1(IMPC)Mbp/MbpMmucd MGI:6493006
ht2
 		Pax6em1(IMPC)Mbp/Pax6+ C57BL/6N-Pax6em1(IMPC)Mbp/MbpMmucd MGI:6696844


Genotype
MGI:6493006
hm1
Allelic
Composition		 Pax6em1(IMPC)Mbp/Pax6em1(IMPC)Mbp
Genetic
Background		 C57BL/6N-Pax6em1(IMPC)Mbp/MbpMmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pax6em1(IMPC)Mbp mutation (1 available); any Pax6 mutation (94 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system

craniofacial
cleft palate ( J:211773 )
IMPC - UCD
facial cleft ( J:211773 )
IMPC - UCD

digestive/alimentary system
cleft palate ( J:211773 )
IMPC - UCD

embryo

growth/size/body
cleft palate ( J:211773 )
IMPC - UCD
facial cleft ( J:211773 )
IMPC - UCD

mortality/aging

vision/eye
anophthalmia ( J:211773 )
IMPC - UCD




Genotype
MGI:6696844
ht2
Allelic
Composition		 Pax6em1(IMPC)Mbp/Pax6+
Genetic
Background		 C57BL/6N-Pax6em1(IMPC)Mbp/MbpMmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pax6em1(IMPC)Mbp mutation (1 available); any Pax6 mutation (94 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
hyperactivity ( J:211773 )
IMPC - UCD

cardiovascular system

embryo

growth/size/body
decreased body length ( J:211773 )
IMPC - UCD

liver/biliary system
small liver ( J:211773 )
IMPC - UCD

nervous system

vision/eye
cornea opacity ( J:211773 )
IMPC - UCD
microphthalmia ( J:211773 )
IMPC - UCD
anophthalmia ( J:211773 )
IMPC - UCD




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory