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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Afdnem1(IMPC)Mbp
endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
MGI:6277063
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Afdnem1(IMPC)Mbp/Afdnem1(IMPC)Mbp C57BL/6N-Afdnem1(IMPC)Mbp/MbpMmucd MGI:6408232
ht2
 		Afdnem1(IMPC)Mbp/Afdn+ C57BL/6N-Afdnem1(IMPC)Mbp/MbpMmucd MGI:6408231


Genotype
MGI:6408232
hm1
Allelic
Composition		 Afdnem1(IMPC)Mbp/Afdnem1(IMPC)Mbp
Genetic
Background		 C57BL/6N-Afdnem1(IMPC)Mbp/MbpMmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Afdnem1(IMPC)Mbp mutation (1 available); any Afdn mutation (84 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:6408231
ht2
Allelic
Composition		 Afdnem1(IMPC)Mbp/Afdn+
Genetic
Background		 C57BL/6N-Afdnem1(IMPC)Mbp/MbpMmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Afdnem1(IMPC)Mbp mutation (1 available); any Afdn mutation (84 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
small heart ( J:211773 )
IMPC - UCD

digestive/alimentary system

embryo

endocrine/exocrine glands

growth/size/body
enlarged kidney ( J:211773 )
IMPC - UCD
enlarged liver ( J:211773 )
IMPC - UCD
enlarged spleen ( J:211773 )
IMPC - UCD

hematopoietic system
enlarged spleen ( J:211773 )
IMPC - UCD
small spleen ( J:211773 )
IMPC - UCD

immune system
enlarged spleen ( J:211773 )
IMPC - UCD
small spleen ( J:211773 )
IMPC - UCD

integument

liver/biliary system
enlarged liver ( J:211773 )
IMPC - UCD

nervous system

renal/urinary system
enlarged kidney ( J:211773 )
IMPC - UCD
cystolithiasis ( J:211773 )
IMPC - UCD

reproductive system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory