Phenotypes associated with this allele

• Allele Symbol: Cox18^em1(IMPC)J
• Allele Name: endonuclease-mediated mutation 1, Jackson
• Allele ID: MGI:6278517
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cox18^em1(IMPC)J/Cox18^em1(IMPC)J	C57BL/6NJ-Cox18^em1(IMPC)J/Mmjax	MGI:6480433
ht2	Cox18^em1(IMPC)J/Cox18^+	C57BL/6NJ-Cox18^em1(IMPC)J/Mmjax	MGI:6461173

Genotype
MGI:6480433

hm1

• Allelic Composition: Cox18^em1(IMPC)J/Cox18^em1(IMPC)J
• Genetic Background: C57BL/6NJ-Cox18^em1(IMPC)J/Mmjax

Data Sources

IMPC Data for Cox18

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

embryonic growth retardation ( J:211773 )

IMPC - JAX

abnormal neural tube closure ( J:211773 )

♂

IMPC - JAX

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - JAX

mortality/aging

prenatal lethality ( J:211773 )

IMPC - JAX

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

nervous system

abnormal neural tube closure ( J:211773 )

♂

IMPC - JAX

Genotype
MGI:6461173

ht2

• Allelic Composition: Cox18^em1(IMPC)J/Cox18⁺
• Genetic Background: C57BL/6NJ-Cox18^em1(IMPC)J/Mmjax

Data Sources

IMPC Data for Cox18

nervous system

decreased prepulse inhibition ( J:211773 )

♂

IMPC - JAX