About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Map3k3tm1.2Mlkn
targeted mutation 1.2, Mark Kahn
MGI:6279294
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Map3k3tm1.1Mlkn/Map3k3tm1.2Mlkn
Nfatc1tm1.1(cre)Bz/Nfatc1+ 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac MGI:6279295


Genotype
MGI:6279295
cn1
Allelic
Composition		 Map3k3tm1.1Mlkn/Map3k3tm1.2Mlkn
Nfatc1tm1.1(cre)Bz/Nfatc1+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map3k3tm1.1Mlkn mutation (0 available); any Map3k3 mutation (27 available)
Map3k3tm1.2Mlkn mutation (0 available); any Map3k3 mutation (27 available)
Nfatc1tm1.1(cre)Bz mutation (0 available); any Nfatc1 mutation (49 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality during organogenesis ( J:238897 )
• embryonic lethality prior to E12.5

cardiovascular system
thin myocardium ( J:238897 )
• thin myocardial cell layer
• however, cardiac jelly is preserved and endocardial-myocardial separation at E10.5 is normal

muscle
thin myocardium ( J:238897 )
• thin myocardial cell layer
• however, cardiac jelly is preserved and endocardial-myocardial separation at E10.5 is normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory