Phenotypes associated with this allele

• Allele Symbol: Ebf2^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6279917
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ebf2^em1(IMPC)Mbp/Ebf2^em1(IMPC)Mbp	C57BL/6N-Ebf2^em1(IMPC)Mbp/MbpMmucd	MGI:6408354
ht2	Ebf2^em1(IMPC)Mbp/Ebf2^+	C57BL/6N-Ebf2^em1(IMPC)Mbp/MbpMmucd	MGI:6461231

Genotype
MGI:6408354

hm1

• Allelic Composition: Ebf2^em1(IMPC)Mbp/Ebf2^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Ebf2^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Ebf2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

no spontaneous movement ( J:211773 )

IMPC - UCD

cardiovascular system

abnormal blood vessel morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

craniofacial

abnormal facial morphology ( J:211773 )

♀

IMPC - UCD

abnormal head shape ( J:211773 )

♀

IMPC - UCD

embryo

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

growth/size/body

abnormal facial morphology ( J:211773 )

♀

IMPC - UCD

abnormal head shape ( J:211773 )

♀

IMPC - UCD

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - UCD

reproductive system

female infertility ( J:211773 )

♀

IMPC - UCD

Genotype
MGI:6461231

ht2

• Allelic Composition: Ebf2^em1(IMPC)Mbp/Ebf2⁺
• Genetic Background: C57BL/6N-Ebf2^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Ebf2

behavior/neurological

decreased locomotor activity ( J:211773 )

♀

IMPC - UCD

no spontaneous movement ( J:211773 )

IMPC - UCD

cardiovascular system

abnormal heart morphology ( J:211773 )

♂

IMPC - UCD

enlarged heart ( J:211773 )

♂

IMPC - UCD

shortened QT interval ( J:211773 )

♂

IMPC - UCD

shortened ST segment ( J:211773 )

♂

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - UCD

enlarged kidney ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

hematopoietic system

abnormal spleen morphology ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

small spleen ( J:211773 )

IMPC - UCD

homeostasis/metabolism

impaired glucose tolerance ( J:211773 )

♀

IMPC - UCD

immune system

abnormal spleen morphology ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

♀

IMPC - UCD

small spleen ( J:211773 )

IMPC - UCD

integument

abnormal skin morphology ( J:211773 )

♀

IMPC - UCD

liver/biliary system

abnormal liver morphology ( J:211773 )

♂

IMPC - UCD

nervous system

abnormal brain morphology ( J:211773 )

♂

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♀

IMPC - UCD

enlarged kidney ( J:211773 )

♀

IMPC - UCD

vision/eye

abnormal retina morphology ( J:211773 )

♀

IMPC - UCD

abnormal vitreous body morphology ( J:211773 )

IMPC - UCD