Phenotypes associated with this allele

• Allele Symbol: Ccdc25^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6279920
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ccdc25^em1(IMPC)Mbp/Ccdc25^em1(IMPC)Mbp	C57BL/6N-Ccdc25^em1(IMPC)Mbp/MbpMmucd	MGI:6408276
ht2	Ccdc25^em1(IMPC)Mbp/Ccdc25^+	C57BL/6N-Ccdc25^em1(IMPC)Mbp/MbpMmucd	MGI:6461129

Genotype
MGI:6408276

hm1

• Allelic Composition: Ccdc25^em1(IMPC)Mbp/Ccdc25^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Ccdc25^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Ccdc25

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

no spontaneous movement ( J:211773 )

IMPC - UCD

cardiovascular system

abnormal placenta vasculature ( J:211773 )

♂

IMPC - UCD

embryo

abnormal placenta morphology ( J:211773 )

♂

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

♂

IMPC - UCD

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

♂

IMPC - UCD

Genotype
MGI:6461129

ht2

• Allelic Composition: Ccdc25^em1(IMPC)Mbp/Ccdc25⁺
• Genetic Background: C57BL/6N-Ccdc25^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Ccdc25

behavior/neurological

no spontaneous movement ( J:211773 )

IMPC - UCD

cardiovascular system

enlarged heart ( J:211773 )

♂

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - UCD

hematopoietic system

small spleen ( J:211773 )

IMPC - UCD

homeostasis/metabolism

impaired glucose tolerance ( J:211773 )

♂

IMPC - UCD

immune system

small spleen ( J:211773 )

IMPC - UCD

liver/biliary system

abnormal liver morphology ( J:211773 )

♂

IMPC - UCD

nervous system

absent optic nerve ( J:211773 )

♀

IMPC - UCD

vision/eye

absent optic nerve ( J:211773 )

♀

IMPC - UCD

cataract ( J:211773 )

IMPC - UCD

abnormal retina morphology ( J:211773 )

IMPC - UCD

abnormal vitreous body morphology ( J:211773 )

IMPC - UCD