endocrine/exocrine glands
N |
• normal thymocyte cellularity
|
hematopoietic system
N |
• normal cellularity of B cells
• normal expression of CD44 and CD62L in CD4+ T cells and CD8+ T cells in spleen
|
• significant decrease in CD8+ T cell numbers in spleen and lymph nodes
• reduced anti-CD3 and anti-CD28 stimulated survival of CD8+ T cells in vitro
• normal Il7-stimulated survival of T cells in vitro
• normal cellularity of NK1.1+ CD3-, NK1.1+ CD3+, CD4+ T cells in spleen and lymph nodes
|
immune system
• significant decrease in CD8+ T cell numbers in spleen and lymph nodes
• reduced anti-CD3 and anti-CD28 stimulated survival of CD8+ T cells in vitro
• normal Il7-stimulated survival of T cells in vitro
• normal cellularity of NK1.1+ CD3-, NK1.1+ CD3+, CD4+ T cells in spleen and lymph nodes
|