All Phenotypes Lrrc19<tm1Ryag> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Lrrc19^tm1Ryag
targeted mutation 1, Rongcun Yang
MGI:6281582

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lrrc19^tm1Ryag/Lrrc19^tm1Ryag	involves: C57BL/6J * C57BL/6NTac	MGI:6294707

Allelic Composition	Lrrc19^tm1Ryag/Lrrc19^tm1Ryag
Genetic Background	involves: C57BL/6J * C57BL/6NTac

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrrc19^tm1Ryag mutation (0 available); any Lrrc19 mutation (20 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased circulating interleukin-6 level ( J:271376 )

• in mice subjected to uropathogenic E. coli infection

decreased circulating tumor necrosis factor level ( J:271376 )

• in mice subjected to uropathogenic E. coli infection

increased susceptibility to bacterial infection ( J:271376 )

• mice subjected to uropathogenic E. coli infection exhibit increased number and decreased clearance of bacteria, and reduced inflammatory response in the kidney compared with wild-type mice

homeostasis/metabolism

decreased circulating interleukin-6 level ( J:271376 )

• in mice subjected to uropathogenic E. coli infection

decreased circulating tumor necrosis factor level ( J:271376 )

• in mice subjected to uropathogenic E. coli infection

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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