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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fasm2Btlr
mutation 2, Bruce Beutler
MGI:6283435
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fasm2Btlr/Fasm2Btlr C57BL/6J-Fasm2Btlr MGI:6283437


Genotype
MGI:6283437
hm1
Allelic
Composition		 Fasm2Btlr/Fasm2Btlr
Genetic
Background		 C57BL/6J-Fasm2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fasm2Btlr mutation (0 available); any Fas mutation (82 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased central memory CD4-positive, alpha-beta T cell number ( J:271891 )
• increased central memory CD4 T cell frequency in the peripheral blood
increased effector memory CD4-positive, alpha-beta T cell number ( J:271891 )
• increased frequencies of effector memory CD8 T cells in CD8 T cells in the peripheral blood

hematopoietic system
increased central memory CD4-positive, alpha-beta T cell number ( J:271891 )
• increased central memory CD4 T cell frequency in the peripheral blood
increased effector memory CD4-positive, alpha-beta T cell number ( J:271891 )
• increased frequencies of effector memory CD8 T cells in CD8 T cells in the peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory