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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Elmo1m3Btlr
mutation 3, Bruce Beutler
MGI:6283440
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Elmo1m3Btlr/Elmo1m3Btlr C57BL/6J-Elmo1m3Btlr MGI:6283445


Genotype
MGI:6283445
hm1
Allelic
Composition		 Elmo1m3Btlr/Elmo1m3Btlr
Genetic
Background		 C57BL/6J-Elmo1m3Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Elmo1m3Btlr mutation (0 available); any Elmo1 mutation (59 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased NK cell number ( J:271894 )
• reduced frequencies of NK cells in the peripheral blood
decreased central memory CD8 positive, alpha-beta T cell number ( J:271894 )
• reduced frequencies of central memory CD8 T cells in CD8 T cells in the peripheral blood
increased CD8-positive, alpha-beta T cell number ( J:271894 )
• increased frequencies of CD8+ T cells in CD3+ T cells in the peripheral blood

hematopoietic system
decreased NK cell number ( J:271894 )
• reduced frequencies of NK cells in the peripheral blood
decreased central memory CD8 positive, alpha-beta T cell number ( J:271894 )
• reduced frequencies of central memory CD8 T cells in CD8 T cells in the peripheral blood
increased CD8-positive, alpha-beta T cell number ( J:271894 )
• increased frequencies of CD8+ T cells in CD3+ T cells in the peripheral blood




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory