Phenotypes associated with this allele

• Allele Symbol: Col3a1^m1Btlr
• Allele Name: mutation 1, Bruce Beutler
• Allele ID: MGI:6283535
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Col3a1^m1Btlr/Col3a1^m1Btlr	C57BL/6J-Col3a1^m1Btlr	MGI:6283537

Genotype
MGI:6283537

hm1

• Allelic Composition: Col3a1^m1Btlr/Col3a1^m1Btlr
• Genetic Background: C57BL/6J-Col3a1^m1Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

increased susceptibility to induced colitis ( J:271973 )

• increased susceptibility to dextran sodium sulfate (DSS)-induced colitis at 10 days after DSS exposure

increased alpha-beta T cell number ( J:271973 )

• increased frequencies of T cells in the peripheral blood

increased CD4-positive, alpha-beta T cell number ( J:271973 )

• increased frequencies of CD4+ T cells in the peripheral blood

increased CD8-positive, alpha-beta T cell number ( J:271973 )

• increased frequencies of CD8+ T cells in the peripheral blood

digestive/alimentary system

increased susceptibility to induced colitis ( J:271973 )

• increased susceptibility to dextran sodium sulfate (DSS)-induced colitis at 10 days after DSS exposure

hematopoietic system

increased alpha-beta T cell number ( J:271973 )

• increased frequencies of T cells in the peripheral blood

increased CD4-positive, alpha-beta T cell number ( J:271973 )

• increased frequencies of CD4+ T cells in the peripheral blood

increased CD8-positive, alpha-beta T cell number ( J:271973 )

• increased frequencies of CD8+ T cells in the peripheral blood