About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Bach2M1Btlr
mutation 1, Bruce Beutler
MGI:6283665
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Bach2M1Btlr/Bach2M1Btlr C57BL/6J-Bach2M1Btlr MGI:6283667


Genotype
MGI:6283667
hm1
Allelic
Composition		 Bach2M1Btlr/Bach2M1Btlr
Genetic
Background		 C57BL/6J-Bach2M1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bach2M1Btlr mutation (0 available); any Bach2 mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased B-1 B cell number ( J:272023 )
• increased frequencies of B1 cells in the peripheral blood
decreased CD4-positive, alpha-beta T cell number ( J:272023 )
• reduced frequencies of CD4+T cells in CD3+T cells in the peripheral blood

hematopoietic system
increased B-1 B cell number ( J:272023 )
• increased frequencies of B1 cells in the peripheral blood
decreased CD4-positive, alpha-beta T cell number ( J:272023 )
• reduced frequencies of CD4+T cells in CD3+T cells in the peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory