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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Bach2M1Btlr
mutation 1, Bruce Beutler
MGI:6283665
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Bach2M1Btlr/Bach2M1Btlr C57BL/6J-Bach2M1Btlr MGI:6283667


Genotype
MGI:6283667
hm1
Allelic
Composition		 Bach2M1Btlr/Bach2M1Btlr
Genetic
Background		 C57BL/6J-Bach2M1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bach2M1Btlr mutation (0 available); any Bach2 mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased B-1 B cell number ( J:272023 )
• increased frequencies of B1 cells in the peripheral blood
decreased CD4-positive, alpha-beta T cell number ( J:272023 )
• reduced frequencies of CD4+T cells in CD3+T cells in the peripheral blood

hematopoietic system
increased B-1 B cell number ( J:272023 )
• increased frequencies of B1 cells in the peripheral blood
decreased CD4-positive, alpha-beta T cell number ( J:272023 )
• reduced frequencies of CD4+T cells in CD3+T cells in the peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory