All Phenotypes Rec114<tm1.2(KOMP)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rec114^{tm1.2(KOMP)Wtsi}
targeted mutation 1.2, Wellcome Trust Sanger Institute
MGI:6284008

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rec114^{tm1.2(KOMP)Wtsi}/Rec114^{tm1.2(KOMP)Wtsi}	involves: C57BL/6N	MGI:6284009

Allelic Composition	Rec114^{tm1.2(KOMP)Wtsi}/Rec114^{tm1.2(KOMP)Wtsi}
Genetic Background	involves: C57BL/6N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rec114^{tm1.2(KOMP)Wtsi} mutation (0 available); any Rec114 mutation (14 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

abnormal meiosis ( J:271216 )

abnormal chromosomal synapsis ( J:271216 )

abnormal synaptonemal complex ( J:271216 )

abnormal oogenesis ( J:271216 )

abnormal ovary morphology ( J:271216 )

• histological and cytological analyses revealed phenotypes similar to those observed in female Rec114^{tm1(KOMP)Wtsi} homozygotes

decreased primary ovarian follicle number ( J:271216 )

decreased primordial ovarian follicle number ( J:271216 )

decreased secondary ovarian follicle number ( J:271216 )

abnormal testis morphology ( J:271216 )

• histological and cytological analyses revealed phenotypes similar to those observed in male Rec114^{tm1(KOMP)Wtsi} homozygotes

abnormal seminiferous tubule morphology ( J:271216 )

decreased testis weight ( J:271216 )

abnormal spermatogenesis ( J:271216 )

endocrine/exocrine glands

abnormal ovary morphology ( J:271216 )

• histological and cytological analyses revealed phenotypes similar to those observed in female Rec114^{tm1(KOMP)Wtsi} homozygotes

decreased primary ovarian follicle number ( J:271216 )

decreased primordial ovarian follicle number ( J:271216 )

decreased secondary ovarian follicle number ( J:271216 )

abnormal testis morphology ( J:271216 )

• histological and cytological analyses revealed phenotypes similar to those observed in male Rec114^{tm1(KOMP)Wtsi} homozygotes

abnormal seminiferous tubule morphology ( J:271216 )

decreased testis weight ( J:271216 )

cellular

abnormal meiosis ( J:271216 )

abnormal chromosomal synapsis ( J:271216 )

abnormal synaptonemal complex ( J:271216 )

abnormal oogenesis ( J:271216 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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