Phenotypes associated with this allele

• Allele Symbol: Tg(Tyro3-GFP)1Sapc
• Allele Name: transgene insertion 1, Sabine Cordes
• Allele ID: MGI:6284562
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	anx/anx Tg(Tyro3-GFP)1Sapc/? Tyro3^m1/Tyro3^m1	involves: C3HeB/FeJLe * C57BL/6J	MGI:6287219

Genotype
MGI:6287219

cx1

• Allelic Composition: anx/anx; Tg(Tyro3-GFP)1Sapc/?; Tyro3^m1/Tyro3^m1
• Genetic Background: involves: C3HeB/FeJLe * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

abnormal body weight ( J:241666 )

• relative to anx homozygotes lacking the Tyro3 wildtype transgene, these mice show a partial rescue of phenotype with the body weight at 21 days of age 83.5% increased on average

mortality/aging

abnormal survival ( J:241666 )

• wildtype mouse Tyro3 partially rescues the anx homozygous phenotype, with anx homozygotes still dying prematurely, but surviving past 35 days of age, having 83.58% of Npy+ soma retained in and properly distributed in the arcuate nucleus at 19 days of age, and showing no or only mild behavioural phentoypes of headweaving, ataxia, or tremors