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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dock2m10Btlr
mutation 10, Bruce Beutler
MGI:6284832
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dock2m10Btlr/Dock2m10Btlr C57BL/6J-Dock2m10Btlr MGI:6284834


Genotype
MGI:6284834
hm1
Allelic
Composition		 Dock2m10Btlr/Dock2m10Btlr
Genetic
Background		 C57BL/6J-Dock2m10Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dock2m10Btlr mutation (0 available); any Dock2 mutation (143 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased B-1b cell number ( J:272404 )
• reduced frequencies of B1b cells in the peripheral blood
increased NK cell number ( J:272404 )
• increased frequencies of NK cells in the peripheral blood

immune system
decreased B-1b cell number ( J:272404 )
• reduced frequencies of B1b cells in the peripheral blood
increased NK cell number ( J:272404 )
• increased frequencies of NK cells in the peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory