About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dock2M14Btlr
mutation 14, Bruce Beutler
MGI:6285155
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dock2M14Btlr/Dock2M14Btlr C57BL/6J-Dock2M14Btlr MGI:6285160


Genotype
MGI:6285160
hm1
Allelic
Composition		 Dock2M14Btlr/Dock2M14Btlr
Genetic
Background		 C57BL/6J-Dock2M14Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dock2M14Btlr mutation (0 available); any Dock2 mutation (143 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal lymphocyte morphology ( J:272438 )
• reduced B to T cell ratios in the peripheral blood
increased CD8-positive, alpha-beta T cell number ( J:272438 )
• increased frequencies of CD8+ T cells in the peripheral blood

hematopoietic system
abnormal lymphocyte morphology ( J:272438 )
• reduced B to T cell ratios in the peripheral blood
increased CD8-positive, alpha-beta T cell number ( J:272438 )
• increased frequencies of CD8+ T cells in the peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory